Analyst Prisco enters Week 10 after a perfect 15-0 straight-up record last week, improving his season mark to 87-48-1. He is 59-74-3 against the spread and aims to climb back to respectability.
Week 10 Picks
New England Patriots at Detroit Lions (-2.5) – Munich, Sunday 9:30 a.m. ET. Prisco expects the Lions' offense to exploit the Patriots' struggling defense. Pick: Lions 30, Patriots 24.
Kansas City Chiefs (-3.5) at Atlanta Falcons – Sunday 1 p.m. ET. The Chiefs snapped a two-game skid; the Falcons were blown out in Madrid. Pick: Chiefs 23, Falcons 17.
Houston Texans at Cleveland Browns (+4.5) – Sunday 1 p.m. ET. Texans' defensive front should dominate. Pick: Texans 21, Browns 20.
Minnesota Vikings at Green Bay Packers (-3.5) – Sunday 1 p.m. ET. Packers' defense limits Kirk Cousins. Pick: Packers 27, Vikings 17.
Jacksonville Jaguars (-10.5) at Tennessee Titans – Sunday 1 p.m. ET. Jaguars rolling after trade deadline moves. Pick: Jaguars 31, Titans 17.
Miami Dolphins (+3.5) at Indianapolis Colts – Sunday 1 p.m. ET. With Malik Willis out, Kyle McCord starts for Miami. Colts win late. Pick: Colts 23, Dolphins 22.
Carolina Panthers at New Orleans Saints (-2.5) – Sunday 1 p.m. ET. Saints make it four straight wins behind Tyler Shough. Pick: Saints 24, Panthers 21.
Buffalo Bills (-8.5) at New York Jets – Sunday 1 p.m. ET. Josh Allen carves up Jets defense. Pick: Bills 34, Jets 21.
Seattle Seahawks (-6.5) at Las Vegas Raiders – Sunday 4:05 p.m. ET. Drew Lock starts again; Raiders have defensive issues. Pick: Seahawks 24, Raiders 16.
Los Angeles Rams at Arizona Cardinals (+9.5) – Sunday 4:05 p.m. ET. Rams without Puka Nacua; Cardinals start rookie Carson Beck. Low-scoring Rams win. Pick: Rams 19, Cardinals 16.
San Francisco 49ers at Dallas Cowboys (+4.5) – Sunday 4:25 p.m. ET. Upset special: Dak Prescott outplays Brock Purdy. Pick: Cowboys 30, 49ers 28.
Pittsburgh Steelers at Cincinnati Bengals (-3.5) – Sunday 8:20 p.m. ET. Joe Burrow and passing game prevail. Pick: Bengals 27, Steelers 21.
Los Angeles Chargers (+4.5) at Baltimore Ravens – Monday 8:15 p.m. ET. Ravens without Lamar Jackson; Jacoby Brissett starts. Close game. Pick: Ravens 20, Chargers 17.
Washington Commanders at New York Giants (-2.5) – Thursday 8:15 p.m. ET. Giants' dominant front contains Jayden Daniels. Pick: Giants 23, Commanders 14.
