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College Football Week 11 Odds and Predictions: Model Favors Wake Forest, Oregon

College Football Week 11 Odds and Predictions: Model Favors Wake Forest, Oregon
World Sports · 06:06:31 - Sunday, 15 November 2026

A Federal Aviation Administration ground stoppage on Friday briefly disrupted travel for several college football programs, but was lifted later in the day, leaving all Week 11 games on schedule except Oklahoma vs. No. 19 Ole Miss, which moves to Sunday at 1 p.m. ET.

The Sooners are listed as 2.5-point favorites in that matchup. Saturday's marquee games include No. 21 LSU vs. No. 6 Texas, with LSU favored by 4.5 points, and No. 9 Indiana vs. No. 18 USC, with Indiana favored by 9.5 points.

SportsLine's computer model, which simulates each FBS game 10,000 times, has released its Week 11 picks. Among its top recommendations: 13th-ranked Wake Forest (+1.5) covers against SMU in a noon ET kickoff. The Demon Deacons are 7-2 against the spread this season and have won five straight by 20-plus points. The model projects Wake Forest covers in over 60% of simulations.

Another highlighted pick: No. 16 Oregon (-10) wins and covers against Michigan at 3:30 p.m. ET. The Ducks have won and covered in back-to-back games against ranked opponents, while Michigan struggled in a loss to Michigan State. The model projects Oregon winning by 16 points and covering in over 60% of simulations, with the over 39.5 total also clearing in over 70% of simulations.

The model also identifies three underdogs projected to win outright in power conference matchups. Full picks for every FBS game are available through SportsLine.

Notable Week 11 odds include: Wake Forest at SMU (-1.5, 60.5), Duke at Miami (-14, 54.5), Northwestern at Ohio State (-14, 45.5), Tennessee at Texas A&M (+1.5, 44.5), Boston College at Notre Dame (-29.5, 51.5), Michigan at Oregon (-10, 39.5), Missouri at Georgia (-16.5, 48.5), USC at Indiana (-9.5, 51.5), Florida at Kentucky (-3, 52.5), Texas at LSU (-4.5, 46.5), South Carolina at Arkansas (+7.5, 51.5), Texas Tech at Oklahoma State (-3.5, 73.5), Utah at Arizona (+1.5, 55.5), and Ole Miss at Oklahoma (-2.5, 48.5) on Sunday.

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