Week 11 of the college football season features several critical matchups for College Football Playoff contenders, with oddsmakers releasing lines for key conference battles. While the slate lacks the ranked-versus-ranked appeal of the previous week, multiple playoff hopefuls face challenging tests.
The Big Ten showdown between USC (7-2) and Indiana (8-1, 5-1 Big Ten) highlights the weekend. Indiana opens as a 7.5-point favorite at home after a bye, while USC arrives off a statement win over Ohio State. A Trojans victory would significantly boost their playoff chances and damage Indiana's resume, which currently lacks a marquee win.
In the SEC, Georgia (-14) hosts Missouri as the last SEC team with fewer than two conference losses and the national title favorite at +240. Georgia crushed Ole Miss 42-7 in Week 10, but the Bulldogs face a Missouri team that competed closely with Texas. Meanwhile, LSU (-4) welcomes Texas in a game that could revive the Tigers' slim playoff hopes with back-to-back wins over Texas and Tennessee.
Other notable lines include Utah (-2.5) at Arizona, Illinois at UCLA (-8.5), and Duke at Miami (-14.5). UCLA aims for a 10-0 start under first-year coach Bob Chesney, while Miami must avoid a letdown after an emotional loss at Notre Dame. Duke has outscored its last two ACC opponents 88-5 behind running back Nate Sheppard.
Additional Week 11 lines feature Northwestern at Ohio State (-10.5), Alabama (-19.5) at Vanderbilt, Michigan at Oregon (-10.5), Boston College at Notre Dame (-30.5), and South Carolina (-7.5) at Arkansas, among others.


