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College Football Week 11 Odds: Indiana Favored Over USC, Georgia Heavy Favorite Against Missouri

College Football Week 11 Odds: Indiana Favored Over USC, Georgia Heavy Favorite Against Missouri
World Sports · 14:28:34 - Sunday, 15 November 2026

Week 11 of the college football season features several critical matchups for College Football Playoff contenders, with oddsmakers releasing lines for key conference battles. While the slate lacks the ranked-versus-ranked appeal of the previous week, multiple playoff hopefuls face challenging tests.

The Big Ten showdown between USC (7-2) and Indiana (8-1, 5-1 Big Ten) highlights the weekend. Indiana opens as a 7.5-point favorite at home after a bye, while USC arrives off a statement win over Ohio State. A Trojans victory would significantly boost their playoff chances and damage Indiana's resume, which currently lacks a marquee win.

In the SEC, Georgia (-14) hosts Missouri as the last SEC team with fewer than two conference losses and the national title favorite at +240. Georgia crushed Ole Miss 42-7 in Week 10, but the Bulldogs face a Missouri team that competed closely with Texas. Meanwhile, LSU (-4) welcomes Texas in a game that could revive the Tigers' slim playoff hopes with back-to-back wins over Texas and Tennessee.

Other notable lines include Utah (-2.5) at Arizona, Illinois at UCLA (-8.5), and Duke at Miami (-14.5). UCLA aims for a 10-0 start under first-year coach Bob Chesney, while Miami must avoid a letdown after an emotional loss at Notre Dame. Duke has outscored its last two ACC opponents 88-5 behind running back Nate Sheppard.

Additional Week 11 lines feature Northwestern at Ohio State (-10.5), Alabama (-19.5) at Vanderbilt, Michigan at Oregon (-10.5), Boston College at Notre Dame (-30.5), and South Carolina (-7.5) at Arkansas, among others.

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