The Week 8 NFL schedule features a full slate of domestic matchups after a week of international games, with several potential postseason rematches including Ravens vs. Bills (-3), Vikings vs. Lions (-3.5), Chiefs vs. Broncos (+1.5), and Bears vs. Seahawks (-3). Notable large spreads include Bengals vs. Titans (+13.5), Jaguars vs. Colts (+10.5), and Rams vs. Chargers (+6.5). The Chargers enter on a nine-game losing streak and are the only winless team against the spread this season.
Model Performance and Methodology
SportsLine's advanced computer model simulates every NFL game 10,000 times and has returned more than $5,000 for $100 players on top-rated NFL picks since its inception. Entering Week 8 of the 2026 season, the model is on a 58-51 run on top-rated picks dating back to 2024. The model has locked in betting picks for every Week 8 matchup based on the latest odds and lines.
Top Week 8 NFL Predictions
One of the model's strongest picks is the Steelers (-3.5, 39) covering at home versus the Browns. Pittsburgh has won 22 straight home games against Cleveland dating back to 2004, is 3-0 against the spread at home this year, and has scored 30-plus points in back-to-back home games. The model projects Pittsburgh to cover well over 60% of the time.
Another highlighted pick: the Rams (-6.5, 45.5) covering versus the Chargers at 4:05 p.m. ET in nearly 60% of simulations. Los Angeles has lost nine straight dating to last season, with Justin Herbert posting twice as many turnovers (12) as touchdowns (6) over that span. The Chargers are also winless against the spread during the streak, while Sean McVay's Rams are 6-2 against the spread in non-conference games since 2025, the second-best mark in the NFL. The over hits 55% of the time in simulations.
Week 8 NFL Betting Odds and Lines
Key lines for the week include: Panthers at Packers (Thursday, final: Packers 27, Panthers 19), Cardinals at Cowboys (DAL -7.5, 54.5), Falcons at Buccaneers (TB -1.5, 43.5), Ravens at Bills (BUF -3, 55.5), Browns at Steelers (PIT -3.5, 39), Colts at Jaguars (JAX -10.5, 45.5), Raiders at Jets (NYJ -1.5, 46.5), Vikings at Lions (DET -3, 46), Titans at Bengals (CIN -13.5, 46.5), Chargers at Rams (LAR -6.5, 45.5), Chiefs at Broncos (KC -1.5, 41.5), Patriots at Dolphins (NE -7, 41.5), Eagles at Commanders (WAS -6, 40.5), and Bears at Seahawks (Monday, SEA -3, 46.5). The model also projects six teams to win by double digits, offering potential value on alternate lines.
