On May 6, 2001, Inter Milan delivered a 6-0 demolition of city rivals AC Milan at the San Siro, a result that remains the heaviest defeat in the history of the Derby della Madonnina. The Nerazzurri's attacking trio of Christian Vieri, Ronaldo, and Clarence Seedorf tore apart a Milan defense that included Paolo Maldini and Alessandro Nesta, with Vieri scoring a hat-trick.
The match came during a turbulent season for Milan, who had won the Serie A title just two years earlier under Alberto Zaccheroni. Inter, coached by Marco Tardelli, capitalized on Milan's defensive frailties and midfield disorganization to produce a performance that has been replayed in highlight reels for over two decades.
For Milan supporters, the 6-0 scoreline represents the nadir of the modern derby rivalry. The defeat sparked a summer overhaul at the club, leading to the arrival of Carlo Ancelotti as manager and the signings of Andrea Pirlo, Rui Costa, and Filippo Inzaghi — foundations of the team that would dominate European football in the following years.
Inter's victory that day was their largest ever over Milan, surpassing the 5-0 win from 1909. The result also marked Ronaldo's first derby goal for Inter, the Brazilian having joined from Barcelona in 1997 but missing previous derbies through injury.
