College football's Week 10 features a slate of high-profile games, and CBS Sports has released its betting picks for the weekend's biggest matchups. The column highlights two "Games of the Week" along with a lock, fade, principle play, and upset pick.
Game of the Week: Miami at No. 11 Notre Dame
Miami's offense takes a hit with wide receiver Malachi Toney sidelined by an ankle injury. The Hurricanes' defense has also struggled recently, allowing 93 points in its last three games against opponents ranked no higher than 47th in points per possession. Notre Dame's offense ranks third nationally in points per drive and success rate at home. The pick: Notre Dame Team Total Over 31.5 (-104) at FanDuel.
Game of the Week: No. 5 Alabama at No. 14 LSU
Alabama's high ranking is questioned, and quarterback Keelon Russell faces a tough test against LSU's defense, which ranks sixth in pressure rate and second in sack rate. Russell was sacked nine times in losses to Georgia and Tennessee. LSU quarterback Sam Leavitt has improved ball security recently. The pick: LSU -5.5 (-110) at FanDuel.
Lock of the Week: Michigan State at Michigan
Michigan's defense tightened in the second half against Rutgers, and new starting quarterback Tommy Carr looked more comfortable. Michigan State has lost six straight and deals with defensive injuries. The pick: Michigan -13.5 (-106) at FanDuel.
Fade of the Week: Cincinnati at No. 17 Houston
Houston had a bye week to recover from a loss to Utah, while Cincinnati was blown out 49-25 by Utah last week after an upset win over Texas Tech. The Bearcats face a third tough opponent in as many weeks on the road. The pick: Houston -10.5 (-112) at DraftKings.
Principle Play of the Week: Texas State at Oregon State
Both offenses rank in the top 15 nationally in scoring, but defenses are porous. Oregon State's offense has slowed recently, Texas State scores fewer points on the road, and rain with 35 mph wind gusts is forecast. The pick: Under 72.5 (-110) at FanDuel.
Upset of the Week: No. 23 Oregon at No. 12 Ohio State
Oregon's offense looked more cohesive after firing its offensive coordinator, while Ohio State starts a true freshman quarterback at home. Oregon's defense has improved, and backup quarterback Dylan Raiola has more experience. The pick: Oregon (+245) to win outright.
Last week's record: Games of the Week 0-2, Lock 1-0, Upset 0-1. Season totals: Games of the Week 10-8 (+0.82 units), Lock 5-4 (+0.52), Upset 2-7 (-3.50), Overall 23-31 (-9.39).
